A basic approach to CKD.
نویسندگان
چکیده
Metabolic acidosis often complicates chronic kidney disease (CKD) and adversely affects bone, nutrition, and metabolism. Phisitkul et al. demonstrate that sodium citrate may ameliorate kidney injury in CKD patients not on dialysis. Further, they provide evidence in humans that treatment lowers urinary endothelin levels, and hence increased endothelin may be part of the mechanism whereby acidosis hastens CKD progression.
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ورودعنوان ژورنال:
- Kidney international
دوره 77 7 شماره
صفحات -
تاریخ انتشار 2010